•The double bubble sign is
seen in infants and represents dilatation of the proximal duodenum and stomach.
It is seen in both radiographs and ultrasound, and can be identified antenatally.
•Causes include :
•Congenital obstruction
•duodenal
web
•duodenal
atresia
•duodenal
stenosis
•annular
pancreas
•Midgut volvulus
•External compression of the duodenum
•The prevalence ~1 in
5,000-10,000 newborns, and
there is no sex-associated difference in prevalence.
•Clinical presentation
•Patients present in early life with symptoms
of
abdominal distension, vomiting and absent bowel movements.
•Associations
•Associated conditions are common and
include:
-Down syndrome:~30% of duodenal atresia cases may have Down syndrome while ~3% of Down syndrome cases may have duodenal atresia
-VACTERL association
-annular pancreas
-other intestinal atresias.
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